The passage of pyrogens and their fragments into a patient’s blood has been shown to cause acute clinical symptoms and contribute to long-term complications. ¹

Even dialysis fluid that falls within the AAMI standard limit can stimulate the synthesis of cytokines. All Fresenius 2008K² systems have an integrated dialysate filter called the DIASAFE® plus which is designed to yield ultrapure dialysate.

The specific characteristics of Fresenius Polysulfone® membrane provide excellent retention of endotoxins. Because of their high molecular weight, microorganisms cannot pass across the membrane, while retention of small lipopolysaccharides (LPS) or non-LPS fragments occurs mainly due to adsorption.

The external mounted DIAFIX™ Lock system makes the filter exchange extremely easy and provides for a safe connection between the filter and the hydraulic components.